What is Clin-Ess?
Clin-Ess is a chemically-defined, non-toxic, animal-component free tissue preservative and transport media. Clin-Ess maintains tissue morphology allowing for many downstream tissue staining options. It also preserves enzymatic activity and protects cells for ex vivo cell culture.
How is Clin-Ess manufactured?
Clin-Ess is produced under ISO-certified and cGMP compliance, and a DMF is available. We can also provide an MSDS and Certificate of Analysis upon request. Clin-Ess is non-toxic and can be disposed of in a standard sink.
What is the shelf-life of Clin-Ess?
The shelf life of unopened Clin-Ess is 1 year from the date of manufacture when stored at 2-8 C, avoiding light. It is recommended to limit the exposure of Clin-Ess to air when using. If Clin-Ess will be used in small amounts, it is recommended to make aliquots for later use.
Does Clin-Ess fix tissue?
Clin-Ess is not a fixative and does not use chemical crosslinking technology or dehydration. Fixatives such as formalin limit the types of analysis that can be performed on preserved tissue. Since Clin-Ess preserves tissue without cross-linking, scientists are able to perform a wide variety of assays - such as proteomic, DNA/RNA analysis and enzymatic assays – after transport.
I want to transport tissue over a few hours. What are the best conditions for transport?
It is recommended to transport tissue on ice whenever possible. If the period of transport is very short (a few hours), room temperature transport might be sufficient, but it is recommended to validate the procedure to ensure that post-transport analysis is not impacted.
There was a problem with shipment, and my shipment was delayed. Can I still use Clin-Ess?
As long as the bottle was not opened and was never frozen, Clin-Ess should be in good condition. If the bottle seal was compromised, or if it is suspected that the bottle was frozen, then it is not recommended to use.
I need to use small amounts of Clin-Ess over a long period of time. What is the best way to use Clin-Ess?
It is recommended to limit the exposure of Clin-Ess to air and light. If Clin-Ess will be used in small amounts, it is recommended to make sterile aliquots for later use.